PIMA1095

MEK1 Monoclonal Antibody (1C1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA1095-Each-of-1 In Stock ₹ 40,940.00

PIMA1095 - Each of 1

₹ 40,940.00

In Stock

Quantity

1

Base Price: ₹ 40,940.00

GST (18%): ₹ 7,369.20

Total Price: ₹ 48,309.20

Antigen

MEK1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.

P31938, Q02750

Gene Symbols

Map2k1

Immunogen

Protein expressed in 293T cell transfected with human MAP2K1 expression vector

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

1C1

Conjugate

Unconjugated

Gene

Map2k1

Gene Alias

CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

26395, 5604

Content And Storage

-20°C

Form

Liquid

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Description

  • MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation
  • MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx
  • Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1
  • It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines
  • Mutations in the gene can lead to cardiofaciocutaneous syndrome.