PIMA110306

CD8 beta Monoclonal Antibody (341), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA110306-Each-of-1 In Stock ₹ 22,027.50

PIMA110306 - Each of 1

₹ 22,027.50

In Stock

Quantity

1

Base Price: ₹ 22,027.50

GST (18%): ₹ 3,964.95

Total Price: ₹ 25,992.45

Antigen

CD8 beta

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P05541

Gene Symbols

Cd8b

Immunogen

CD8 positive Wistar rat splenic T cell hybridomas

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

341

Conjugate

Unconjugated

Gene

Cd8b

Gene Alias

CD8; CD8 antigen 37 kDa chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8a; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; CD8B1; CD8beta; CD8BP; LEU2; Leu-2; LY3; Ly-3; Ly-C; Lymphocyte antigen 3; Lyt3; Lyt-3; MAL; OX-8 membrane antigen; p32; P37; T lymphocyte surface glycoprotein beta chain; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

24931

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system
  • The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules
  • The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain
  • Both alpha and beta chains share significant homology to immunoglobulin variable light chains
  • This gene encodes the CD8 beta chain isoforms
  • Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described
  • A pseudogene, also located on chromosome 2, has been identified.