HLA-G (soluble) Monoclonal Antibody (2A12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA110358-Each-of-1 | In Stock | ₹ 31,328.00 |
PIMA110358 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,328.00
GST (18%): ₹ 5,639.04
Total Price: ₹ 36,967.04
Antigen
HLA-G (soluble)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P17693
Gene Symbols
HLA-G
Immunogen
C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
2A12
Conjugate
Unconjugated
Gene
HLA-G
Gene Alias
acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species
Mouse
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3135
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- This antibody does not cross-react with the full-length HLA-G1 isoform and therefore is able to distinguish between secreted HLA-G5 and HLA-G6 isoforms from shedded HLA-G1
- Purity is > 95% by SDS-PAGE
- HLA-G belongs to the HLA class I heavy chain paralogues
- This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
- The heavy chain is anchored in the membrane
- HLA-G is expressed on fetal derived placental cells
- The heavy chain is approximately 45 kDa and its gene contains 8 exons
- Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.