PIMA124990

MBP Monoclonal Antibody (Clone 14), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA124990-Each-of-1 In Stock ₹ 50,507.50

PIMA124990 - Each of 1

₹ 50,507.50

In Stock

Quantity

1

Base Price: ₹ 50,507.50

GST (18%): ₹ 9,091.35

Total Price: ₹ 59,598.85

Antigen

MBP

Classification

Monoclonal

Concentration

Conc. not determined

Formulation

tissue culture supernatant with 0.09% sodium azide

Gene Accession No.

P02686, P02687, P02688, P04370

Gene Symbols

MBP

Immunogen

Synthetic peptide corresponding to residues 36-50 of bovine Myelin Basic Protein.

Regulatory Status

RUO

Gene ID (Entrez)

17196, 24547, 4155, 618684

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Frozen)

Clone

Clone 14

Conjugate

Unconjugated

Gene

MBP

Gene Alias

20 kDa microtubule-stabilizing protein; C76307; golli mbp; Golli-mbp; Golli-MBP; myelin basic protein; Golli-Mbp; myelin basic protein; myelin basic protein S; Hmbpr; MBP; MBP S; Mbps; MGC99675; microtubule-stabilizing protein; mLd; MOBP; Myelin A1 protein; myelin basic protein; myelin basic protein Golli-mbp; myelin basic protein S; myelin deficient; myelin membrane encephalitogenic protein; Myelin P1 protein; myelin-associated oligodendrocyte basic protein; R75289; shi; shiverer; Unknown (protein for IMAGE:7984318); unnamed protein product

Host Species

Rat

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Bovine, Human, Multi-species, Mouse, Rat

Product Type

Antibody

Isotype

IgG2b

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Description

  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system
  • However, MBP-related transcripts are also present in the bone marrow and the immune system
  • These mRNAs arise from the long MBP gene (otherwise called &quoteGolli-MBP&quote) that contains 3 additional exons located upstream of the classic MBP exons
  • Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products
  • The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons
  • They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence
  • The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins
  • This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.