CD48 Monoclonal Antibody (MCR OX-45), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA170025-Each-of-1 | In Stock | ₹ 25,587.50 |
PIMA170025 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,587.50
GST (18%): ₹ 4,605.75
Total Price: ₹ 30,193.25
Antigen
CD48
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P10252
Gene Symbols
Cd48
Immunogen
Rat T cell blasts (stimulated purified T helper cells with allogeneic irradiated rat spleen cells).
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
MCR OX-45
Conjugate
Unconjugated
Gene
Cd48
Gene Alias
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
245962
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-70025 detects CD48 in rat samples
- MA1-70025 has been successfully used in flow cytometry procedures
- The MA1-70025 immunogen is rat T cell blasts (stimulated purified T helper cells with allogeneic irradiated rat spleen cells)
- CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily that includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others
- These molecules bind to the same or another members of the Ig family, thus mediating homotypic or heterotypic adhesion
- CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2
- 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation
- Further, signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases
- CD48 is strongly expressed on lymphocytes and monocytes, weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium
- CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2
- 2B4-CD48 interaction may be involved in the pathology of allergic airway diseases and provide a pharmacological target for the treatment of diseases such as allergic rhinitis and asthma.