Staphylococcus Enterotoxin A Monoclonal Antibody (D99G), Invitrogen™

Description

• The MA1-7480 antibody reacts with Staphylococcus Enterotoxin toxin A capture in bacterial and infected tissue samples
• See related products for paired antibody
• MA1-7480 has been successfully used in ELISA applications
• The MA1-7480 antibody was raised against Staphylococcus Toxin A
• MA1-74347 recognises Staphylococcus aureus enterotoxin type A
• Staphylococcus aureus produces several different types of enterotoxins (SE’s)
• The SE’s are short, soluble proteins that are highly stable and resistant to most proteolytic enzymes
• They belong to a family of pyrogenic toxins and as such cause an increase in body temperature, immunosuppression and non-specific T-cell proliferation
• These activities are referred to as superantigen activity and results from the interaction of SE’s with T-cell antigen receptors and the major histocompatibility complex (MHC) on antigen presenting cells
• In addition to their superantigen activity, SE’s are also emetics (they cause vomiting)
• The SE’s are important in food poisoning
• Enterotoxin A is one of the SE’s most commonly identified in clinical isolates
• MA1-74347 may be used as a capture antibody in ELISA assays for S
• aureus enterotoxin A in combination with MCA2848 as a detection agent.