PIMA182074

CD14 Monoclonal Antibody (TüK4), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA182074-Each-of-1 In Stock ₹ 43,387.50

PIMA182074 - Each of 1

₹ 43,387.50

In Stock

Quantity

1

Base Price: ₹ 43,387.50

GST (18%): ₹ 7,809.75

Total Price: ₹ 51,197.25

Antigen

CD14

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.

P08571, Q28680, Q95122

Gene Symbols

Cd14

Immunogen

Proprietary Immunogen.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Camelid, Canine, Cynomolgus Monkey, Feline, Goat, Human, Mink, Ovine, Porcine, Rabbit

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

TüK4

Conjugate

FITC

Gene

Cd14

Gene Alias

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100008983, 100037938, 100861226, 101096132, 102129342, 102177056, 281048, 443216, 607076, 929

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Mouse anti human CD14 antibody, clone TÜK4 recognizes the human CD14 cell surface antigen
  • CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils
  • CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form
  • CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein
  • The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles
  • Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes
  • Alternative splicing results in multiple transcript variants encoding the same CD14 isoform
  • Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.