CD45RC Monoclonal Antibody (MIL15), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA182383-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA182383 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
CD45RC
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
tissue culture supernatant with 5-10% FBS and 0.09% sodium azide
Gene Accession No.
0
Gene Symbols
Ptprc
Immunogen
Cells isolated from porcine mesenteric lymph node.
Regulatory Status
RUO
Gene ID (Entrez)
100522631
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
MIL15
Conjugate
Unconjugated
Gene
Ptprc
Gene Alias
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species
Mouse
Quantity
2 mL
Primary or Secondary
Primary
Target Species
Porcine
Product Type
Antibody
Isotype
IgM
Related Products
Description
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Mouse anti Pig CD45RC, clone MIL5 recognizes a restricted CD45 epitope encoded by the CD45 C exon and will bind and immunoprecipitate both the approximately 210 kDa RC and approximately 226 kDa RAC isoforms
- CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor
- It acts as a positive regulator of T-cell coactivation upon binding to DPP4
- The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first
- Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN
- Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.