PIMA182815

C4BPA Monoclonal Antibody (10-07), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA182815-Each-of-1 In Stock ₹ 68,129.50

PIMA182815 - Each of 1

₹ 68,129.50

In Stock

Quantity

1

Base Price: ₹ 68,129.50

GST (18%): ₹ 12,263.31

Total Price: ₹ 80,392.81

Antigen

C4BPA

Classification

Monoclonal

Concentration

1.15 mg/mL

Formulation

BBS with 0.1% sodium azide; pH 8.4

Gene Accession No.

P04003

Gene Symbols

C4BPA

Immunogen

Native human C4 binding protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

ELISA, Flow Cytometry

Clone

10-07

Conjugate

Unconjugated

Gene

C4BPA

Gene Alias

AI195242; C4b-binding protein; C4b-binding protein alpha chain; C4bp; C4bpa; complement component 4 binding protein; complement component 4 binding protein alpha; complement component 4 binding protein, alpha; proline-rich protein; PRP; RP11-164O23.4

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

722

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Mouse anti human C4bp monoclonal antibody, clone 051-198.6.3 (10-07), recognizes complement component 4 binding protein (C4bp)
  • There are three variants of C4bp, composed of alpha and beta chains
  • There are 3 variants of Complement component 4 binding protein (C4bp), which is composed of alpha and beta chains
  • The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain
  • The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain
  • C4bp regulates the activation of the classical complement pathway
  • It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b
  • C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a
  • Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S
  • C4bp is expressed in the blood serum.