NOTCH1 Monoclonal Antibody (A6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA191405-Each-of-1 | In Stock | ₹ 50,685.50 |
PIMA191405 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,685.50
GST (18%): ₹ 9,123.39
Total Price: ₹ 59,808.89
Antigen
NOTCH1
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.1% sodium azide; pH 7.4
Gene Accession No.
P46531, Q01705
Gene Symbols
Notch1
Immunogen
Recombinant protein encoding the ligand binding region of human Notch 1
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone
A6
Conjugate
Unconjugated
Gene
Notch1
Gene Alias
9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18128, 4851
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- MA1-91405 has been successfully used in flow cytometry and immunohistochemistry (paraffin tissue) applications
- Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10 - 20 min followed by cooling at room temperature for 20 min
- A suggested positive control for this product is pancreas
- The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region
- Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures
- The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1
- Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).