SAFB Monoclonal Antibody (4i59), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA191526-Each-of-1 | In Stock | ₹ 49,884.50 |
PIMA191526 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
SAFB
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 0.15M NaCl, 30% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q15424
Gene Symbols
SAFB
Immunogen
synthetic peptide CPEARDKEDGRKF, corresponding to amino acids 345 to 357 of SAFB.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
4i59
Conjugate
Unconjugated
Gene
SAFB
Gene Alias
3110021E02Rik; 5330423C17Rik; AU018122; D18386; DKFZp779C1727; E130307D12; glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; Safb; SAF-B; Safb1; SAF-B1; scaffold attachment factor B; scaffold attachment factor B1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
6294
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recommended positive controls: An independent laboratory has shown HET/SAFB to be immunoprecipitated from MCF-7 and HepG2 cell lysates
- This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA)
- This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein
- Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR
- The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes
- It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis
- This gene is arranged head-to-head with a similar gene whose product has the same functions
- Multiple transcript variants encoding different isoforms have been found for this gene.