ITGA4 Monoclonal Antibody (TA-2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA49D7-Each-of-1 | In Stock | ₹ 45,968.50 |
PIMA49D7 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
ITGA4
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P13612
Gene Symbols
ITGA4
Immunogen
Rat 150 kD alpha4 chain of VLA-4 (CD49d).
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunohistochemistry, Neutralization
Clone
TA-2
Conjugate
Unconjugated
Gene
ITGA4
Gene Alias
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
311144, 3676
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- MA49D7 targets CD49d in FACS, IHC, and Neu applications and shows reactivity with Rat and Human samples
- The MA49D7 immunogen is rat 150 kD alpha4 chain of VLA-4 (CD49d)
- MA49D7 detects CD49d which has a predicted molecular weight of approximately 111 kDa
- This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
- The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
- Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
- Alpha4 chain associates with either beta1 or beta7 chain
- It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
- These ligands included Madcam, VCAM, and fibronectin
- Madcam is known as the principal ligand for integrin alpha4beta7
- Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.