PIMA511516

Caspase 3 Monoclonal Antibody (3CSP01 (7.1.44)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA511516-Each-of-1 In Stock ₹ 53,578.00

PIMA511516 - Each of 1

₹ 53,578.00

In Stock

Quantity

1

Base Price: ₹ 53,578.00

GST (18%): ₹ 9,644.04

Total Price: ₹ 63,222.04

Antigen

Caspase 3

Classification

Monoclonal

Concentration

0.8 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P42574

Gene Symbols

CASP3

Immunogen

Recombinant full length human Caspase 3 protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

3CSP01 (7.1.44)

Conjugate

Unconjugated

Gene

CASP3

Gene Alias

A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

836

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-11516 targets Caspase 3 in immunohistochemistry (paraffin), immunoprecipitation, and Western blot applications and shows reactivity with Human samples
  • The MA5-11516 immunogen is recombinant full length human Caspase 3 protein
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme
  • This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10
  • It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease
  • Alternative splicing of this gene results in two transcript variants that encode the same protein.