IGF1R alpha Monoclonal Antibody (24-31), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA513799-Each-of-1 | In Stock | ₹ 50,463.00 |
PIMA513799 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,463.00
GST (18%): ₹ 9,083.34
Total Price: ₹ 59,546.34
Antigen
IGF1R alpha
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P08069
Gene Symbols
Igf1r
Immunogen
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
24-31
Conjugate
Biotin
Gene
Igf1r
Gene Alias
A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3480
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-13799 targets IGF-1 Receptor alpha in ELISA, ICC/IF, IHC (P) and immunoprecipitation applications and shows reactivity with Human samples
- The MA5-13799 immunogen is iGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
- IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1)
- It binds IGF1 with high affinity and IGF2/insulin with lower affinity
- Activated IGF1R is involved in cell growth and survival control
- IGF1R is crucial for tumor transformation and survial of malignant cells
- Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.