PIMA514344
E2F1 Monoclonal Antibody (KH95), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514344-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA514344 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
E2F1
Classification
Monoclonal
Concentration
0.4 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q01094, Q61501
Gene Symbols
E2F1
Immunogen
Recombinant human E2F-1 protein
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
KH95
Conjugate
Unconjugated
Gene
E2F1
Gene Alias
E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
13555, 1869
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-14344 targets E2F-1 Transcription Factor in gel shift, immunofluorescence, immunohistochemistry (paraffin), immunoprecipitation, and Western blot applications and shows reactivity with Human and mouse samples
- The MA5-14344 immunogen is recombinant human E2F-1 protein
- The protein encoded by this gene is a member of the E2F family of transcription factors
- The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
- The E2F proteins contain several evolutionally conserved domains found in most members of the family
- These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
- This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain
- This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner
- It can mediate both cell proliferation and p53-dependent/independent apoptosis.