TCF7 Monoclonal Antibody (G.452.9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514972-Each-of-1 | In Stock | ₹ 44,544.50 |
PIMA514972 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,544.50
GST (18%): ₹ 8,018.01
Total Price: ₹ 52,562.51
Antigen
TCF7
Classification
Monoclonal
Concentration
163 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P36402, Q00417
Gene Symbols
TCF7
Immunogen
Synthetic peptide corresponding to a region surrounding Leu160 of human TCF1/TCF7 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
G.452.9
Conjugate
Unconjugated
Gene
TCF7
Gene Alias
AI465550; HMG-box; OTTHUMP00000159390; OTTHUMP00000159391; T cell factor-1; T-cell factor 1; T-cell specific; T-cell-specific transcription factor 1; Tcf1; TCF-1; Tcf7; TCF-7; Transcription factor 7; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T cell specific; transcription factor 7, T-cell specific
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21414, 363595, 6932
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with LEF1
- TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation
- Necessary for the survival of CD4+ and CD8+ immature thymocytes
- Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role
- TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene
- It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes
- TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.