PIMA515032

Nonphospho-4EBP1 (Thr46) Monoclonal Antibody (E.638.3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515032-Each-of-1 In Stock ₹ 47,481.50

PIMA515032 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Nonphospho-4EBP1 (Thr46)

Classification

Monoclonal

Concentration

138 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

Q13541, Q60876, Q62622

Gene Symbols

EIF4EBP1

Immunogen

Synthetic peptide corresponding to residues surrounding Thr46 of human 4E-BP1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot

Clone

E.638.3

Conjugate

Unconjugated

Gene

EIF4EBP1

Gene Alias

4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116636, 13685, 1978

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This gene encodes one member of a family of translation repressor proteins
  • The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs
  • Interaction of this protein with eIF4E inhibits complex assembly and represses translation
  • This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.