MEK1 Monoclonal Antibody (K.971.4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515093-Each-of-1 | In Stock | ₹ 44,366.50 |
PIMA515093 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,366.50
GST (18%): ₹ 7,985.97
Total Price: ₹ 52,352.47
Antigen
MEK1
Classification
Monoclonal
Concentration
227 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P31938, Q01986, Q02750
Gene Symbols
Map2k1
Immunogen
Full length MEK1 proteins
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Immunoprecipitation, Western Blot
Clone
K.971.4
Conjugate
Unconjugated
Gene
Map2k1
Gene Alias
CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
170851, 26395, 5604
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with MEK2 and other MAP kinase kinases
- MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation
- MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx
- Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1
- It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines
- Mutations in the gene can lead to cardiofaciocutaneous syndrome.