Phospho-p38 MAPK alpha (Thr180, Tyr182) Monoclonal Antibody (F.52.8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515177-Each-of-1 | In Stock | ₹ 53,400.00 |
PIMA515177 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,400.00
GST (18%): ₹ 9,612.00
Total Price: ₹ 63,012.00
Antigen
Phospho-p38 MAPK alpha (Thr180, Tyr182)
Classification
Monoclonal
Concentration
71 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
O61443, P47811, P70618, Q16539
Gene Symbols
MAPK14, p38b
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding pThr180/Tyr182 of human p38 MAPK
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
F.52.8
Conjugate
Unconjugated
Gene
MAPK14
Gene Alias
186F5S; anon-sts23; BG:DS00797.3; CG7393; CG7393-PA; CRK1; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; Csbp2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Dm p38b; Dmel\CG7393; Dmel_CG7393; Dmp38b; Dp38; D-p38; D-p38 MAPK; Dp38b; D-p38b; EC 2.7.11.24; ERK1; ERT2; ESTS:186F5S; etID18993.8; Exip; fk28c03; hm:zeh1243; Hog; I79_016605; LD24658p; MAP 14; MAP kinase 1; MAP kinase 11; MAP kinase 14; MAP kinase 14A; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38a; MAP kinase p38alpha; MAP kinase p38b; MAPK; MAPK 11; MAPK 14; MAPK 14A; MAPK1 antibody; Mapk11; Mapk14; mapk14a; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 14; mitogen-activated protein kinase 14a; Mitogen-activated protein kinase p38 alpha; mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; mitogen-activated protein kinase p38a; Mitogen-activated protein kinase p38b; MK14; Mpk34C; Mxi2; OTTHUMP00000216563; OTTHUMP00000216566; P38; p38 alpha; p38 alpha/Mxi2; p38 beta; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38 mitogen-activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38B; p38b MAP kinase; p38beta; p38beta2; p38b-PA; p38Hog; p38Kb; p38MAPK; PRKM11; Prkm14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; RP1-179N16.5; Sapk2; Sapk2A; SAPK2b; stress-activated p38b MAP kinase; stress-activated protein kinase 2A; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38; wu:fk28c03; zeh1243; zp38a
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1432, 26416, 34780, 81649
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with the phosphorylated forms of either p42/44 MAPK or SAPK/JNK
- MAPK14 (p38 alpha) is a member of the stress-activated protein kinase class of MAPKs
- The p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation, and other signals
- p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs
- There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors
- When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation
- Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK
- Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.