c-Met Monoclonal Antibody (K.845.5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515198-Each-of-1 | In Stock | ₹ 53,756.00 |
PIMA515198 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,756.00
GST (18%): ₹ 9,676.08
Total Price: ₹ 63,432.08
Antigen
c-Met
Classification
Monoclonal
Concentration
1000 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P08581, P16056, P97523
Gene Symbols
MET
Immunogen
Synthetic peptide corresponding to residues surrounding Tyr1234 of human Met
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunoprecipitation, Western Blot
Clone
K.845.5
Conjugate
Unconjugated
Gene
MET
Gene Alias
AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17295, 24553, 4233
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies
- After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3
- There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC
- MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation
- It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling
- MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.