PIMA515333
Thioredoxin 1 Monoclonal Antibody (1H6H6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515333-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA515333 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
Thioredoxin 1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P10599
Gene Symbols
TXN
Immunogen
Purified recombinant fusion protein with Thioredoxin (TRX) tag.
Regulatory Status
RUO
Gene ID (Entrez)
7295
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Clone
1H6H6
Conjugate
Unconjugated
Gene
TXN
Gene Alias
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15333 targets Thioredoxin (TRX) in indirect ELISA, WB applications and shows reactivity with Human samples
- The MA5-15333 immunogen is purified recombinant fusion protein with Thioredoxin (TRX) tag
- MA5-15333 detects Thioredoxin (TRX) which has a predicted molecular weight of approximately 12kDa
- Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells
- Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site
- The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds
- Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor
- The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations
- Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53, NF-kB and AP-1 (T1-151)
- Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.