PIMA515352

PRAK Monoclonal Antibody (7H10B4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515352-Each-of-1 In Stock ₹ 50,062.50

PIMA515352 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

PRAK

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q8IW41

Gene Symbols

MAPKAPK5

Immunogen

Purified recombinant fragment of PRAK expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

8550

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

7H10B4

Conjugate

Unconjugated

Gene

MAPKAPK5

Gene Alias

MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15352 targets PRAK in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
  • The MA5-15352 immunogen is purified recombinant fragment of PRAK expressed in E
  • Coli
  • MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines
  • Activity of this kinase is regulated by p38 alpha and p38 beta
  • The protein encoded by PRAK is a member of the serine/threonine kinase family
  • In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta
  • In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites
  • Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.