IKK epsilon Monoclonal Antibody (6B4B5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515377-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515377 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
IKK epsilon
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
Q14164
Gene Symbols
IKBKE
Immunogen
Purified recombinant fragment of IKBKE (aa1-257) expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
9641
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Clone
6B4B5
Conjugate
Unconjugated
Gene
IKBKE
Gene Alias
AW558201; I-kappa-B kinase epsilon; Ikbke; IKKE; IKK-E; IKKepsilon; IKK-epsilon; IKKI; IKK-i; IKK-related kinase epsilon; inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of kappaB kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151; RP11-534L20.1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15377 targets IKBKE in indirect ELISA, WB applications and shows reactivity with Human samples
- The MA5-15377 immunogen is purified recombinant fragment of IKBKE (aa1-257) expressed in E
- Coli
- IKBKE is an activator of nuclear factor-kappa-B
- Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death
- NF-kappa-B is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses
- NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli
- NF-kappa-B is associated with Ikappa-B proteins in the cell cytoplasm, which inhibit NF-kappa-B activity
- Ikappa-B is phosphorylated by Ikappa-B kinase (IKK) complex that contains IKK-a, IKK-b, and IKK-gamma
- A novel molecule in the IKK complex was recently identified and designated IKK-iota/IKK-i
- IKK epsilon is required for the activation of NF-kappa-B by PMA and T cell receptors but not by TNF-a and IL-1
- IKK-iota/IKK-i message is expressed in a variety of tissues and is inducible by TNF-a, IL-1, and LPS.