CRYAB Monoclonal Antibody (1D11C6E6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515383-Each-of-1 | In Stock | ₹ 52,643.50 |
PIMA515383 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,643.50
GST (18%): ₹ 9,475.83
Total Price: ₹ 62,119.33
Antigen
CRYAB
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P02511
Gene Symbols
Cryab
Immunogen
Purified recombinant fragment of CRYAB (aa1-175) expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
1410
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone
1D11C6E6
Conjugate
Unconjugated
Gene
Cryab
Gene Alias
2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- MA5-15383 targets CRYAB in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15383 immunogen is purified recombinant fragment of CRYAB (aa1-175) expressed in E
- Coli
- Lens proteins consist almost entirely of crystallins (about 95%)
- Crystallins are also found vertebrate skeletal muscle tissue
- In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
- The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
- Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
- There are at least 5 different proteins comprising the beta-crystallins
- The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
- Alpha-Crystallin comprises 40% of total lens protein composition
- In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
- It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
- Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.