PIMA515484

Ki-67 Monoclonal Antibody (9C12B2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515484-Each-of-1 In Stock ₹ 55,180.00

PIMA515484 - Each of 1

₹ 55,180.00

In Stock

Quantity

1

Base Price: ₹ 55,180.00

GST (18%): ₹ 9,932.40

Total Price: ₹ 65,112.40

Antigen

Ki-67

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P46013

Gene Symbols

Mki67

Immunogen

Purified recombinant fragment of Ki167 (aa3118-3256) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

4288

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

9C12B2

Conjugate

Unconjugated

Gene

Mki67

Gene Alias

antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15484 targets Ki67 in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15484 immunogen is purified recombinant fragment of Ki167 (aa3118-3256) expressed in E
  • Coli
  • Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases
  • The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus
  • Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase
  • Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis
  • Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms
  • In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index
  • The correlation between low Ki-67 index and histologically low-grade tumors is strong
  • Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.