ETS1 Monoclonal Antibody (8A8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515609-Each-of-1 | In Stock | ₹ 52,821.50 |
PIMA515609 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,821.50
GST (18%): ₹ 9,507.87
Total Price: ₹ 62,329.37
Antigen
ETS1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P14921
Gene Symbols
ETS1
Immunogen
Purified recombinant fragment of human ETS1 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
2113
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
8A8
Conjugate
Unconjugated
Gene
ETS1
Gene Alias
AI196000; AI448617; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; avian erythroblastosis virus E26 oncogene 1; c-ets protein; c-ets1; c-ets-1; c-ets-1 oncogene; c-ets-1 protein; c-ets-alpha; c-ets-beta; D230050P06; E26 avian leukemia oncogene 1, 5' domain; Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); ets protein; ETS proto-oncogene 1, transcription factor; Ets1; ETS-1; ETS-1A; ETS-1B; Ets-1Delta(III-VI); Etsoncb; EWSR2; FLJ10768; oncoprotein; p54; p54 transcription factor; protein C-ets-1; TNFAIP3 interacting protein 1; TNIP1; Tpl1; transforming protein p54/c-ets-1; transforming protein p68/c-ets-1; tumor progression locus 1; unnamed protein product; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1; virion-associated nuclear-shuttling protein
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15609 targets ETS1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples
- The MA5-15609 immunogen is purified recombinant fragment of human ETS1 expressed in E
- Coli.<br>
- MA5-15609 detects ETS1 which has a predicted molecular weight of approximately 50.4kDa
- ETS1 (c-Ets-1; v-ets erythroblastosis virus E26 oncogene homlog 1 (avian); ETS-1; EWSR2; p54), a 441 A
- A protein, is a member of DNA-binding ETS protein family
- It is a multifunctional protein consisting of an N-terminal pointed domain, a central transactivation domain and 2 auto inhibitory domains flanked on both sides of conserved C-terminal Ets domain
- It interacts with factors including PEBP2alphaA, p300/CBP and mediates transactivation of Osteopontin, Presenilin-1, Stromelysin and Collagenase
- It is activated by Ras/MAPK signaling and its expression is up-regulated in resting T-cells
- Its activity is modulated by various factors including AP-1, Sp-1, c-myb and MafB
- Sp100 activates ETS1 in nuclear bodies
- It interacts with EAP1/Daxx and causes repression of MMP1 and BCL2 transactivation
- It interacts with STAT6 and modulates Socs-1 expression induced by IL-4
- It interacts with GATA3 and positively regulates Tax-1 dependent IL-5 expression.