PIMA515700

KLHL1 Monoclonal Antibody (3A8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515700-Each-of-1 In Stock ₹ 50,062.50

PIMA515700 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

KLHL1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q9JI74, Q9NR64

Gene Symbols

KLHL1

Immunogen

Purified recombinant fragment of human KLHL1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

290426, 57626, 93688

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

3A8

Conjugate

Unconjugated

Gene

KLHL1

Gene Alias

FLJ30047; kelch like family member 1; kelch-l like; kelch-like 1; kelch-like family member 1; kelch-like protein 1; KIAA1490; Klhl1; Mayven-related protein 2; mKIAA1490; MRP2; RP11-394C23.1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15700 targets KLHL1 in indirect ELISA, IF and WB applications and shows reactivity with Human, Mouse and Rat samples
  • The MA5-15700 immunogen is purified recombinant fragment of human KLHL1 expressed in E
  • Coli
  • MA5-15700 detects KLHL1 which has a predicted molecular weight of approximately 82kDa
  • In Western blot, MA5-15700 did not detect KLHL1 in whole rat brain lysates, but detected KLHL1 in hippocampal neuronal cell lysates
  • The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues
  • The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins
  • Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.