Dectin 1 (soluble) Monoclonal Antibody (2A11), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516483-Each-of-1 | In Stock | ₹ 23,362.50 |
PIMA516483 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,362.50
GST (18%): ₹ 4,205.25
Total Price: ₹ 27,567.75
Antigen
Dectin 1 (soluble)
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
Q6QLQ4
Gene Symbols
Clec7a
Immunogen
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry
Clone
2A11
Conjugate
PE
Gene
Clec7a
Gene Alias
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
56644
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
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Description
- Reconstitute with 1 mL of distilled water
- After reconstitution, store product undiluted at 4oC in the dark
- Once reconstituted, this product has a shelf life of approx
- 18 months
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1
- Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1
- CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells
- It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM)
- CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response
- Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.