CD49f Monoclonal Antibody (450-30A), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516517-Each-of-1 | In Stock | ₹ 44,811.50 |
PIMA516517 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
CD49f
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.
P23229
Gene Symbols
Itga6
Immunogen
alpha 6 beta 4 integrin purified from A431 cells
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
450-30A
Conjugate
FITC
Gene
Itga6
Gene Alias
5033401O05Rik; AI115430; Alpha6p; CD49 antigen-like family member F; CD49f; DKFZp686J01244; FLJ18737; integrin alpha 6; integrin alpha-6; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; integrin alpha6B; integrin subunit alpha 6; integrin, alpha 6; Itga6; ITGA6B; LOW QUALITY PROTEIN: integrin alpha-6; Processed integrin alpha-6; VLA-6
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3655
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form
Liquid
Related Products
Description
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- CDf (Integrin alpha-6, ITGA6) is the integrin alpha chain alpha 6 protein
- Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain
- A given chain may combine with multiple partners resulting in different integrins
- For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6
- Integrins are known to participate in cell adhesion as well as cell-surface mediated signaling
- Two transcript variants encoding different isoforms have been found for CDf
- Functionally, integrins are cell surface receptors that interact with the extracellular matrix and mediate intracellular signals that affect cellular shape, mobility, and progression through the cell cycle in response to the extracellular matrix
- Integrin receptors are composed of alpha and beta subunits, and form structural and functional linkages between the ECM (extra-cellular matrix) and intracellular cytoskeletal linker proteins
- Signaling mediated by Intergrin/ECM interactions are also integrated with cellular responses to growth factor signaling to regulate cellular proliferation, cytoskeletal reorganization and other responses necessary for cellular survival
- CDf is predominantly expressed by epithelia, and plays a critical structural role in the hemidesmosome
- More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals
- Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells.