CD21 Monoclonal Antibody (CA2.1D6), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516609-Each-of-1 | In Stock | ₹ 94,607.00 |
PIMA516609 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 94,607.00
GST (18%): ₹ 17,029.26
Total Price: ₹ 1,11,636.26
Antigen
CD21
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
0
Gene Symbols
CR2
Immunogen
The details of the immunogen for this antibody are not currently available.
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Canine, Equine, Feline
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
CA2.1D6
Conjugate
PE
Gene
CR2
Gene Alias
C3b/C4b receptor; C3-binding protein; C3BR; C3DR; C4BR; CD21; CD35; CD35 antigen; cell surface receptor for C3d; complement C3b/C4b receptor 1 (Knops blood group); complement C3d receptor; Complement C3d receptor (C3DR); complement C3d receptor 2; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3d/Epstein Barr virus) receptor 2; complement component 3b/4b receptor 1 (Knops blood group); complement component 3d receptor 2; complement component receptor 2; complement receptor 1 long isoform; complement receptor 2; complement receptor type 1; complement receptor type 1-like protein; complement receptor type 2; Complement Receptor type 2 (CR2); CR; CR1; Cr-1; CR1-L; Cr2; Cr-2; CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; expressed in B lymphocytes; KN; Knops blood group antigen; LOW QUALITY PROTEIN: complement receptor type 1; SLEB9
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
101094393, 102149469, 490269
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
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Description
- MA5-16609 should not be used with MA5-16605 (mouse anti-canine CD3), in dual color flow cytometry, due to non-specific interactions between the two reagents
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Reconstitute with 1 mL of distilled water
- After reconstitution, store product undiluted at 4oC in the dark
- Mouse anti Canine CD21 antibody, clone CA2.1D6 recognizes canine CD21, also known as Complement receptor type 2
- CD21 is a cell surface antigen expressed by canine B lymphocytes
- CD21 (complement receptor 2, CR2, C3D receptor, EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen
- CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens
- CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions
- A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands
- CD21 functions as receptor for C3d, C3dg and iC3b complement components, for EBV and for IFNalpha
- CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation
- Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9)
- Alternatively, spliced transcript variants encoding different isoforms of CD21 have been found.