ITGA2 Monoclonal Antibody (DX5), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516648-Each-of-1 | In Stock | ₹ 27,723.50 |
PIMA516648 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,723.50
GST (18%): ₹ 4,990.23
Total Price: ₹ 32,713.73
Antigen
ITGA2
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
Q62469
Gene Symbols
Itga2
Immunogen
RIL-2 propogated NK1.1+ cells from C57BL/6 mice.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgM
Applications
Flow Cytometry
Clone
DX5
Conjugate
FITC
Gene
Itga2
Gene Alias
alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
16398
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family
- It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex
- VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways
- It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation
- CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells
- It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.