TREM1 Monoclonal Antibody (L5-B8.2A12.3A12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516765-Each-of-1 | In Stock | ₹ 66,082.50 |
PIMA516765 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 66,082.50
GST (18%): ₹ 11,894.85
Total Price: ₹ 77,977.35
Antigen
TREM1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9JKE2
Gene Symbols
TREM1
Immunogen
Mouse TREM-1 Fc fusion protein
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
L5-B8.2A12.3A12
Conjugate
Unconjugated
Gene
TREM1
Gene Alias
CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
58217
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing
- We recommend the use of acetone fixation for frozen sections
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- This product is a low-endotoxin, preservative-free formulation
- Endotoxin level is <0.01EU/ug
- Rat anti Mouse Trem-1 antibody, clone L5-B8.2A12.3A12 recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes
- TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers
- It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response
- TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.