Factor VII Monoclonal Antibody (RFF-VII/2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516932-Each-of-1 | In Stock | ₹ 55,625.00 |
PIMA516932 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,625.00
GST (18%): ₹ 10,012.50
Total Price: ₹ 65,637.50
Antigen
Factor VII
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P08709
Gene Symbols
F7
Immunogen
Purified Factor VII
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Radioimmune Assays (RIA), Western Blot
Clone
RFF-VII/2
Conjugate
Unconjugated
Gene
F7
Gene Alias
AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2155
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody binds to a conformational epitope and will not bind to reduced Factor VII
- Mouse anti Human Factor VII antibody, clone RFF-VII/2 recognizes Factor VII, a serine protease found circulating in the blood
- It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor
- Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis
- This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis
- Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond
- In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa
- Defects in F7 production can cause coagulopathy.