BID Monoclonal Antibody (3C5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517034-Each-of-1 | In Stock | ₹ 55,180.00 |
PIMA517034 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,180.00
GST (18%): ₹ 9,932.40
Total Price: ₹ 65,112.40
Antigen
BID
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P55957
Gene Symbols
BID
Immunogen
Purified recombinant full length human BID protein expressed in E. Coli
Regulatory Status
RUO
Gene ID (Entrez)
637
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
3C5
Conjugate
Unconjugated
Gene
BID
Gene Alias
2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-17034 targets BID in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples
- The MA5-17034 immunogen is purified recombinant fragment of human BID expressed in E
- Coli
- MA5-17034 detects BID which has a predicted molecular weight of approximately 22kDa
- BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2
- Bid is a member of the BCL-2 family of cell death regulators
- BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release
- BID is also a pro-apoptotic member of the Bcl 2 family
- BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand
- Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis
- BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.