PIMA517052

CDK2 Monoclonal Antibody (1A6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517052-Each-of-1 In Stock ₹ 51,753.50

PIMA517052 - Each of 1

₹ 51,753.50

In Stock

Quantity

1

Base Price: ₹ 51,753.50

GST (18%): ₹ 9,315.63

Total Price: ₹ 61,069.13

Antigen

CDK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P24941, P97377

Gene Symbols

CDK2

Immunogen

Purified recombinant fragment of human CDK2 expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

1A6

Conjugate

Unconjugated

Gene

CDK2

Gene Alias

A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1017, 12566

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-17052 targets CDK2 in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human and Mouse samples
  • The MA5-17052 immunogen is purified recombinant fragment of human CDK2 expressed in E
  • Coli
  • MA5-17052 detects CDK2 which has a predicted molecular weight of approximately 33.9kDa
  • CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO
  • CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus
  • In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity
  • CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle
  • The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication
  • Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo
  • Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.