FceR1 alpha Monoclonal Antibody (1F2A9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517074-Each-of-1 | In Stock | ₹ 49,884.50 |
PIMA517074 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
FceR1 alpha
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P12319, P20489
Gene Symbols
FCER1A
Immunogen
Purified recombinant fragment of human FCER1A (amino acids:42-103) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Western Blot
Clone
1F2A9
Conjugate
Unconjugated
Gene
FCER1A
Gene Alias
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
14125, 2205
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17074 targets FCER1A in indirect ELISA, FACS and WB applications and shows reactivity with Human samples
- The MA5-17074 immunogen is purified recombinant fragment of human FCER1A (amino acids:42-103) expressed in E
- Coli
- MA5-17074 detects FCER1A which has a predicted molecular weight of approximately 29.6kDa
- FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE
- Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one β and two additional subunits
- The latter two are required for signal transduction activity
- The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response
- When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released
- The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma
- The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.