PIMA517107

KEAP1 Monoclonal Antibody (7G4B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517107-Each-of-1 In Stock ₹ 50,062.50

PIMA517107 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

KEAP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q14145

Gene Symbols

Keap1

Immunogen

Purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

7G4B10

Conjugate

Unconjugated

Gene

Keap1

Gene Alias

cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9817

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-17107 targets KEAP1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples
  • The MA5-17107 immunogen is purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E
  • Coli
  • MA5-17107 detects KEAP1 which has a predicted molecular weight of approximately 69.7kDa
  • This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain
  • Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus
  • This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase
  • Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.