PIMA517198
VAV1 Monoclonal Antibody (2E11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517198-Each-of-1 | In Stock | ₹ 55,625.00 |
PIMA517198 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,625.00
GST (18%): ₹ 10,012.50
Total Price: ₹ 65,637.50
Antigen
VAV1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P15498
Gene Symbols
VAV1
Immunogen
Purified recombinant fragment of human VAV1 (amino acids: 121-324) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Western Blot
Clone
2E11
Conjugate
Unconjugated
Gene
VAV1
Gene Alias
oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
7409
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17198 targets VAV1 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples
- The MA5-17198 immunogen is purified recombinant fragment of human VAV1 (amino acids: 121-324) expressed in E
- Coli
- MA5-17198 detects VAV1 which has a predicted molecular weight of approximately 98.3kDa
- This gene encodes the coiled-coil containing protein optineurin
- Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma
- Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction
- Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins
- Alternative splicing results in multiple transcript variants encoding the same protein.