PIMA517608

VAMP1/VAMP2 Monoclonal Antibody (SP10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517608-Each-of-1 In Stock ₹ 47,481.50

PIMA517608 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

VAMP1/VAMP2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P23763, P63027

Gene Symbols

VAMP1, VAMP2

Immunogen

Human Synaptobrevin 1 (aa 1-118) and Synaptobrevin 2(aa 33-96).

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgM

Applications

ELISA, Flow Cytometry, Western Blot

Clone

SP10

Conjugate

Unconjugated

Gene

VAMP1

Gene Alias

RATVAMPB; RATVAMPIR; SPAX1; SYB; SYB1; SYB2; synaptobrevin 1; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin-1; Synaptobrevin-2; Vamp1; VAMP-1; VAMP2; VAMP-2; vesicle associated membrane protein 1; vesicle associated membrane protein 2; Vesicle-associated membrane protein (synaptobrevin 2); vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1); vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6843, 6844

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-17608 targets VAMP/synaptobrevin in ELISA, FACS, and WB applications and shows reactivity with Human samples
  • The MA5-17608 immunogen is human Synaptobrevin 1 (aa 1-118) and Synaptobrevin 2(aa 33-96)
  • Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis
  • VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis
  • Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue
  • VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle
  • The two isoforms are differentially expressed in various tissues and their level may depend on differentiation
  • VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells
  • Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy
  • Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.