PIMA517910

OX40L Monoclonal Antibody (OX89), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517910-Each-of-1 In Stock ₹ 39,338.00

PIMA517910 - Each of 1

₹ 39,338.00

In Stock

Quantity

1

Base Price: ₹ 39,338.00

GST (18%): ₹ 7,080.84

Total Price: ₹ 46,418.84

Antigen

OX40L

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P43488

Gene Symbols

Tnfsf4

Immunogen

CD4.CD134L chimeric protein

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry

Clone

OX89

Conjugate

Unconjugated

Gene

Tnfsf4

Gene Alias

Ath1; Ath-1; atherosclerosis 1; CD134 ligand; CD134L; CD252; glycoprotein Gp34; GP34; OX40 antigen ligand; OX40 ligand; OX40L; OX-40L; OX4OL; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); tax-transcriptionally activated glycoprotein 1 ligand; TNFSF4; TNLG2B; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor (ligand) superfamily, member 4; tumor necrosis factor ligand 2B; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4; TXGP1; Txgp1l

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

22164

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-17910 targets CD134L/OX40L in FACS, FN, and IHC applications and shows reactivity with Mouse samples
  • The MA5-17910 immunogen is cD4.CD134L chimeric protein
  • The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein
  • It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells
  • TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells
  • TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells
  • It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma
  • TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.