CD45RC Monoclonal Antibody (IBL-8), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517988-Each-of-1 | In Stock | ₹ 20,781.50 |
PIMA517988 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,781.50
GST (18%): ₹ 3,740.67
Total Price: ₹ 24,522.17
Antigen
CD45RC
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene Accession No.
P06800
Gene Symbols
Ptprc
Immunogen
Mouse Spleen Cells
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
IBL-8
Conjugate
PE
Gene
Ptprc
Gene Alias
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
19264
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor
- It acts as a positive regulator of T-cell coactivation upon binding to DPP4
- The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first
- Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN
- Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.