Methyl-PP2A alpha (Leu309) Monoclonal Antibody (2A10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA518072-Each-of-1 | In Stock | ₹ 59,897.00 |
PIMA518072 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,897.00
GST (18%): ₹ 10,781.46
Total Price: ₹ 70,678.46
Antigen
Methyl-PP2A alpha (Leu309)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P63330, P63331, P67775
Gene Symbols
PPP2CA
Immunogen
A KLH-coupled peptide with the sequence: KLH-C-βA-RRTPDYFL-OMe
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunoprecipitation, Western Blot
Clone
2A10
Conjugate
Unconjugated
Gene
PPP2CA
Gene Alias
B55-GAMMA; hypothetical protein; IMYPNO; IMYPNO1; Methyl-PPP2CA; MGC33570; PP2A; PP2A alpha; PP2A C terminal; PP2A L9; PP2A Leucine 9; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; Ppp2ca; PR52; PR55G; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 catalytic subunit alpha; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2,catalytic subunit alpha isozyme; protein phosphatase 2A alpha subunit; protein phosphatase 2A catalytic subunit alpha isoform; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A; protein phosphatase-2A-alpha; R75353; replication protein C; RP-C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; unnamed protein product
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
19052, 24672, 5515
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody recognizes the C-terminal methylated form of PP2A (C subunit)
- The c-terminal sequence, as well as the carboxy-methylation, is 100% conserved in human, mouse and yeast
- Western blot results show a band at 36 kDa, which matches the predicted molecular weight
- The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast
- In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis
- A group of proteins that are intimately involved in this process are the protein phosphatases
- In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit
- Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C
- The PP2A family comprises subfamily members PP2A alpha and PP2A beta
- An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.