PIMA518076

Emerin Monoclonal Antibody (MANEM1(5D10)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA518076-Each-of-1 In Stock ₹ 55,625.00

PIMA518076 - Each of 1

₹ 55,625.00

In Stock

Quantity

1

Base Price: ₹ 55,625.00

GST (18%): ₹ 10,012.50

Total Price: ₹ 65,637.50

Antigen

Emerin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P50402

Gene Symbols

Emd

Immunogen

Recombinant Human Emerin aa 1-188

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rabbit

Product Type

Antibody

Isotype

IgG1

Applications

Immunoblot, Immunocytochemistry, Western Blot

Clone

MANEM1(5D10)

Conjugate

Unconjugated

Gene

Emd

Gene Alias

AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100328755, 2010

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody does not cross-react with mouse samples
  • This target has a predicted molecular weight of 29 kDa
  • Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
  • The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
  • Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
  • The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
  • A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
  • A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
  • Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.