CD55 Monoclonal Antibody (MEM-118), Alexa Fluor™ 488, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA518146-Each-of-1 | In Stock | ₹ 38,181.00 |
PIMA518146 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,181.00
GST (18%): ₹ 6,872.58
Total Price: ₹ 45,053.58
Antigen
CD55
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Gene
CD55
Gene Alias
CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1604
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MEM-118
Formulation
TBS with 0.2% BSA and 15mM sodium azide; pH 8.0
Gene Accession No.
P08174
Gene Symbols
CD55
Immunogen
HPB-ALL human T cell line
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgM
Related Products
Description
- This antibody recognizes an epitope in the SCR4 domain of CD55
- CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade
- Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can regulate complement when bound to CD97
- In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis
- CD55 is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail
- In other cells, the apparent molecular weight is somewhat larger for CD55 and has a substantial content of O-glycans
- CD55 binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways
- CD55 carries the Cromer related blood group antigens
- Two alternatively spliced transcripts encoding CD55 have been identified, and the predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels
- CD55 has been studied to have a role in prostate cancer growth and survival.