PIMA524456

VPS8 Monoclonal Antibody (2C8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524456-Each-of-1 In Stock ₹ 47,481.50

PIMA524456 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

VPS8

Classification

Monoclonal

Conjugate

Unconjugated

Gene

VPS8

Gene Alias

AI315068; AU040738; im:7166005; KIAA0804; mKIAA0804; RGD1309443; si:dkey-24b15.1; vacuolar protein sorting 8 homolog; vacuolar protein sorting 8 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 8 homolog; VPS8; VPS8 CORVET complex subunit; VPS8 subunit of CORVET complex; VPS8, CORVET complex subunit; zgc:158695

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23355

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

2C8

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

Q8N3P4

Gene Symbols

VPS8

Immunogen

KIAA0804 (NP_001009921, 1329 a.a. ∽ 1428 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Peptide Sequence: RITPSQVKMS PSYHQSKGDP TAKKGTSEPV LDPQQIQAFD QLCRLYRGSS RLALLTELSQ NRSSESYRPF SGSQSAPAFN SIFQNENFQL QLIPPPVTED Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway
  • Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion
  • The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290)
  • Functions predominantly in APPL1-containing endosomes (PubMed:25266290)
  • [UniProt]