PIMA524548

TRIB2 Monoclonal Antibody (1D11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524548-Each-of-1 In Stock ₹ 47,481.50

PIMA524548 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

TRIB2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

Q92519

Gene Symbols

Trib2

Immunogen

TRIB2 (AAH02637, 1 a.a. ∽ 343 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

Applications

ELISA, Immunoprecipitation, Western Blot

Clone

1D11

Conjugate

Unconjugated

Gene

Trib2

Gene Alias

AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

28951

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Peptide Sequence: MNIHRSTPIT IARYGRSRNK TQDFEELSSI RSAEPSQSFS PNLGSPSPPE TPNLSHCVSC IGKYLLLEPL EGDHVFRAVH LHSGEELVCK VFDISCYQES LAPCFCLSAH SNINQITEII LGETKAYVFF ERSYGDMHSF VRTCKKLREE EAARLFYQIA SAVAHCHDGG LVLRDLKLRK FIFKDEERTR VKLESLEDAY ILRGDDDSLS DKHGCPAYVS PEILNTSGSY SGKAADVWSL GVMLYTMLVG RYPFHDIEPS SLFSKIRRGQ FNIPETLSPK AKCLIRSILR REPSERLTSQ EILDHPWFST DFSVSNSAYG AKEVSDQLVP DVNMEENLDP FFN This gene encodes one of three members of the Tribbles family
  • The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function
  • The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes
  • This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin
  • It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia
  • Alternatively spliced transcript variants have been found for this gene.