PHD1 Recombinant Rabbit Monoclonal Antibody (3G4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524853-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA524853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
PHD1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q6AYU4, Q91YE2, Q96KS0
Gene Symbols
EGLN2
Immunogen
Recombinant PHD1.
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
3G4
Conjugate
Unconjugated
Gene
EGLN2
Gene Alias
0610011A13Rik; C85656; egl nine homolog 2; egl-9 family hypoxia inducible factor 2; egl-9 family hypoxia-inducible factor 2; Egln2; EIT6; EIT-6; Estrogen-induced tag 6; falkor; HIF-1alpha prolyl-4-hydroxylase-1; HIF-P4H 1; Hif-p4h-1; HIFPH1; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-1; HPH-3; Hypoxia-inducible factor prolyl hydroxylase 1; Ier4; immediate early response 4; P4H1; Phd1; PHD-1; Prolyl hydroxylase domain-containing protein 1; SM-20
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
112398, 112406, 308457
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Prolyl hydroxylase domain proteins HIF PHD1, HIF PHD2 and HIF PHD3 (known as PHD1, PHD2 and PHD3 in rodents, respectively) can hydroxylate HIF-alpha subunits
- Hypoxia-inducible factor (HIF) is a transcriptional regulator important in several aspects of oxygen homeostasis
- The prolyl hydroxylases catalyze the posttranslational formation of 4-hydroxyproline in HIF-alpha proteins
- HIF PHD1, which is widely expressed, with highest levels of expression in testis, functions as a cellular oxygen sensor and is important in cell growth regulation
- HIF PHD1 can localize to the nucleus or the cytoplasm and is also detected in hormone responsive tissues, such as normal and cancerous mammary, ovarian and prostate epithelium
- HIF PHD1 is encoded by EGLN2, which maps to chromosome 19q13
- 3.