PIMA524891

SOX17 Monoclonal Antibody (OTI2G8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524891-Each-of-1 In Stock ₹ 52,287.50

PIMA524891 - Each of 1

₹ 52,287.50

In Stock

Quantity

1

Base Price: ₹ 52,287.50

GST (18%): ₹ 9,411.75

Total Price: ₹ 61,699.25

Antigen

SOX17

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9H6I2

Gene Symbols

SOX17

Immunogen

Human recombinant protein fragment corresponding to amino acids 177-414 of SOX17 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2G8

Conjugate

Unconjugated

Gene

SOX17

Gene Alias

HMG transcription factor SOX17; HMG-box transcription factor Sox17; Sox17; Sox-17; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box 17; SRY-box containing gene 17; SRY-box transcription factor 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; transcription factor SOX-17; LOW QUALITY PROTEIN: transcription factor SOX-17; VUR3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

486955, 64321

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors
  • It acts as a transcription regulator that binds target promoter DNA and bends the DNA
  • It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'
  • SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling
  • It promotes degradation of activated CTNNB1
  • SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm
  • Mutations in the gene can result in vesicoureteral reflux.