HIPPI Monoclonal Antibody (OTI4F6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525044-Each-of-1 | In Stock | ₹ 52,465.50 |
PIMA525044 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,465.50
GST (18%): ₹ 9,443.79
Total Price: ₹ 61,909.29
Antigen
HIPPI
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9NWB7
Gene Symbols
IFT57
Immunogen
Full length human recombinant protein of IFT57 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4F6
Conjugate
Unconjugated
Gene
IFT57
Gene Alias
4833420A15Rik; dermal papilla-derived protein 8; DERP8; Esrrbl1; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; FLJ10147; HIP1 protein interactor; HIP1-interacting protein; Hippi; huntingtin interacting protein-1 interacting protein; huntingtin-interacting protein-1 protein interactor; IFT57; intraflagellar transport 57; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog; MHS4R2; Vestrogen-related receptor beta like 1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55081
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- HIPPI is required for the formation of cilia
- Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway
- Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis
- Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.