PANK2 Monoclonal Antibody (OTI3H9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525152-Each-of-1 | In Stock | ₹ 52,287.50 |
PIMA525152 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,287.50
GST (18%): ₹ 9,411.75
Total Price: ₹ 61,699.25
Antigen
PANK2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9BZ23
Gene Symbols
PANK2
Immunogen
Full length human recombinant protein of PANK2 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Canine, Human, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI3H9
Conjugate
Unconjugated
Gene
PANK2
Gene Alias
4933409I19Rik; AI642621; C20orf48; Hallervorden-Spatz syndrome; HARP; hPanK2; HSS; NBIA1; PANK2; pantothenate kinase 2; pantothenate kinase 2 (Hallervorden-Spatz syndrome); pantothenate kinase 2, mitochondrial; pantothenate kinase 2, mitochondrial isoform 1 preproprotein; pantothenate kinase 2, mitochondrial-like; pantothenic acid kinase 2; PKAN
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
296167, 477168, 80025
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine
- CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism
- In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable
- Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS)
- PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain
- Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).